Methyl 3-cyclopropyl-3-oxopropionate
3-Cyclopropyl-3-oxopropionic acid methyl ester
CAS: 32249-35-7
Molecular Formula: C7H10O3
Methyl 3-cyclopropyl-3-oxopropionate - Names and Identifiers
| Name | 3-Cyclopropyl-3-oxopropionic acid methyl ester |
| Synonyms | Methyl 3-cyclopropyl-3-oxopropionate methyl 3-cyclopropyl-3-oxopropanoate 3-Cyclopropyl-3-oxopropionic acid methyl ester 3-Cyclopropyl-3-Oxo-Propionic Acid Methyl Ester |
| CAS | 32249-35-7 |
| InChI | InChI=1/C7H10O3/c1-10-7(9)4-6(8)5-2-3-5/h5H,2-4H2,1H3 |
Methyl 3-cyclopropyl-3-oxopropionate - Physico-chemical Properties
| Molecular Formula | C7H10O3 |
| Molar Mass | 142.15 |
| Density | 1.175g/cm3 |
| Boling Point | 192.983°C at 760 mmHg |
| Flash Point | 74.14°C |
| Vapor Presure | 0.476mmHg at 25°C |
| pKa | 10.59±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.475 |
| MDL | MFCD00274090 |
| Use | Methyl 3-cyclopropyl-3-oxopropionate is a reagent for the synthesis of pitavastatin. |
Methyl 3-cyclopropyl-3-oxopropionate - Upstream Downstream Industry
| Downstream Products | Pitavastatin Methyl Ester Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate |
Methyl 3-cyclopropyl-3-oxopropionate - Introduction
3-Cyclopropyl-3-oxopropionic acid methyl ester is an organic compound with the chemical formula C7H10O3. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: 3-Cyclopropyl-3-oxopropionic acid methyl ester is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ethanol, methanol and Ether solvents.
-Melting point: The melting point of 3-Cyclopropyl-3-oxopropionic acid methyl ester is -25°C.
-Boiling point: Its boiling point is 172-176 ℃.
Use:
3-Cyclopropyl-3-oxopropionic acid methyl ester is often used as an intermediate in organic synthesis reactions in the laboratory to prepare other compounds. It can also be used as an important raw material in the field of drug synthesis and agriculture.
Method:
The preparation method of 3-Cyclopropyl-3-oxopropionic acid methyl ester can be obtained by the reaction of cyclopropyl-propanedione and methanol under base catalysis. Specific steps are:
1. Mix cyclopropyl-propanedione and methanol in a certain molar ratio.
2. The esterification reaction is carried out under the catalysis of alkali.
3. After completion of the reaction, 3-Cyclopropyl-3-oxopropionic acid methyl ester was obtained by distillation.
Safety Information:
Pay attention to the following security considerations when using 3-Cyclopropyl-3-oxopropionic acid methyl ester:
-It is a flammable liquid and should be kept away from open flames and high temperatures.
-Contact with skin can cause irritation and allergic reactions, so gloves and protective clothing should be worn during operation.
-Avoid inhaling its vapor or gas, and operate in a well-ventilated place.
-If inhaled or exposed to the compound, rinse immediately with water and seek medical attention.
Nature:
-Appearance: 3-Cyclopropyl-3-oxopropionic acid methyl ester is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ethanol, methanol and Ether solvents.
-Melting point: The melting point of 3-Cyclopropyl-3-oxopropionic acid methyl ester is -25°C.
-Boiling point: Its boiling point is 172-176 ℃.
Use:
3-Cyclopropyl-3-oxopropionic acid methyl ester is often used as an intermediate in organic synthesis reactions in the laboratory to prepare other compounds. It can also be used as an important raw material in the field of drug synthesis and agriculture.
Method:
The preparation method of 3-Cyclopropyl-3-oxopropionic acid methyl ester can be obtained by the reaction of cyclopropyl-propanedione and methanol under base catalysis. Specific steps are:
1. Mix cyclopropyl-propanedione and methanol in a certain molar ratio.
2. The esterification reaction is carried out under the catalysis of alkali.
3. After completion of the reaction, 3-Cyclopropyl-3-oxopropionic acid methyl ester was obtained by distillation.
Safety Information:
Pay attention to the following security considerations when using 3-Cyclopropyl-3-oxopropionic acid methyl ester:
-It is a flammable liquid and should be kept away from open flames and high temperatures.
-Contact with skin can cause irritation and allergic reactions, so gloves and protective clothing should be worn during operation.
-Avoid inhaling its vapor or gas, and operate in a well-ventilated place.
-If inhaled or exposed to the compound, rinse immediately with water and seek medical attention.
Last Update：2024-04-09 20:44:15
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Product Name: 3-Cyclopropyl-3-oxopropionic Acid Methyl Ester Visit Supplier Webpage Request for quotationCAS: 32249-35-7
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Product Name: 3-Cyclopropyl-3-oxopropionate methyl ester Request for quotation
CAS: 32249-35-7
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Mobile: +86-13651600618
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CAS: 32249-35-7
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Mobile: +86-13651600618
QQ: 2850607228
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View History
Downstream Products for Methyl 3-cyclopropyl-3-oxopropionate
Pitavastatin Methyl Ester
Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate
Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate